Renal scarring in spinal cord injury: a progressive process?
نویسندگان
چکیده
منابع مشابه
Reducing Pericyte-Derived Scarring Promotes Recovery after Spinal Cord Injury
CNS injury often severs axons. Scar tissue that forms locally at the lesion site is thought to block axonal regeneration, resulting in permanent functional deficits. We report that inhibiting the generation of progeny by a subclass of pericytes led to decreased fibrosis and extracellular matrix deposition after spinal cord injury in mice. Regeneration of raphespinal and corticospinal tract axon...
متن کاملCell Therapy in Spinal Cord Injury: a Mini- Reivew
Spinal cord injury (SCI) is a debilitating disease which leads to progressive functional damages. Because of limited axonal regeneration in the central nervous system, there is no or little recovery expected in the patients. Different cellular and molecular approaches were investigated in SCI animal models. Cellular transplantation of stem cells can potentially replace damaged tissue and provid...
متن کاملA progressive compression model of thoracic spinal cord injury in mice: function assessment and pathological changes in spinal cord
Non-traumatic injury accounts for approximately half of clinical spinal cord injury, including chronic spinal cord compression. However, previous rodent spinal cord compression models are mainly designed for rats, few are available for mice. Our aim is to develop a thoracic progressive compression mice model of spinal cord injury. In this study, adult wild-type C57BL/6 mice were divided into tw...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Spinal Cord
سال: 2005
ISSN: 1362-4393,1476-5624
DOI: 10.1038/sj.sc.3101831